Preimplantation Genetic Screening

Ensuring Healthy Embryos for Successful Pregnancy

Preimplantation Genetic Screening (PGS) is a new reproductive technology that is used to screen the embryos for chromosomal abnormality before implantation. It is performed to ensure maximum chances of a successful pregnancy while reducing the likelihood of genetic disorders and failure of implantation.

Who Should Apply Preimplantation Genetic Screening?

PGS is best suited for individuals and couples who:

• Experience recurrent miscarriages – Usually linked with chromosomal abnormalities.
• Are of advanced maternal age (35+ years) – Genetic disorders are more likely.
• Have experienced repeated IVF failure – PGS increases embryo selection.
• Want to reduce risk of genetic disease – Detects chromosomal aneuploidies (e.g., Down syndrome, Turner syndrome).
• Are planning single embryo transfer (SET) – Offers guarantee that healthiest embryo is chosen.

The Step-by-Step Process of  Preimplantation Genetic Screening:

1. IVF & Embryo Development

• Eggs are retrieved, fertilized in a laboratory, and developed into embryos (Day 3 or Day 5).
• Genetic analysis is done only on the healthy embryos.

2. Embryo Biopsy – Cell Removal for Testing

• A small number of cells are removed from every embryo gently without harming its development.
• It is performed on Day 5 or Day 6 when the embryos are at the blastocyst stage.

3. Genetic Analysis – Screening for Chromosomal Abnormalities

• The cells are retrieved and are studied with detailed chromosomal screening using newer genetic tests (Next-Generation Sequencing, Array CGH, or PCR-based testing).
• Identifies missing, excess, or abnormal chromosomes.

4. Embryo Selection & Freezing

• Normal chromosomally healthy embryos are transferred.
• The remaining healthy embryos can be frozen for future use.

5. Embryo Transfer – Placing the Best Embryo

• One good-quality embryo is placed in the uterus.
• It is painless and non-surgical.

6. Pregnancy Test & Follow-Up

• Pregnancy test is conducted 10-14 days post-transfer.
• Early pregnancy is closely monitored and cared for.

Benefits of Preimplantation Genetic Screening:

• Increases IVF Success Rates – Improves implantation and pregnancy rate.
• Reduces the Risk of Genetic Disorders – Screens for chromosomal abnormalities.
• Reduces Miscarriage Rate – Prevents chromosomally defective pregnancies.
• Promotes Single Embryo Transfer (SET) – Lowers multiple pregnancy risk.
• Improves Family Planning – Allows couples to make informed reproductive choices.

Risks & Considerations

• Not a Guaranteed Outcome of Pregnancy – PGS only improves embryo selection and not implantation.
• Rare Chances of Damage to the Embryo – While minimal, there is always the slightest chance of affecting embryo viability.

Why Medcy IVF Hospital for PGS Treatment?

• Genetic Testing Lab of International Standards – Accurate and reliable embryo screening.
• Experts in Fertility & Genetics – to provide precise embryo selection.
• Personalized Fertility Plans – According to your medical and genetic background.
• Detailed IVF & PGS Integration – Seamless treatment experience with highest success rates.